The 2025 generation

Hana Aliee¹, Leire Bejarano-Bosque^{2

3}, Roger Castells-Graells⁴, Deborah Caswell⁵, Mirco Julian Friedrich^{6

7}, Carino Gurjao⁸, Li Ren Kong^{9

10

11}, Shuang Liu¹², Simone Minnie^{13

14}, Reineke A Schoot¹⁵, Zefang Tang¹⁶

Affiliations

¹ Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK. hana.aliee@cruk.cam.ac.uk.
² Biogipuzkoa Health Research Institute, San Sebastián, Spain. leire.bejaranobosque@bio-gipuzkoa.eus.
³ Ikerbasque Basque Foundation for Science, Bilbao, Spain. leire.bejaranobosque@bio-gipuzkoa.eus.
⁴ Spanish National Cancer Research Centre (CNIO), Madrid, Spain. rcastellsg@cnio.es.
⁵ Respiratory Medicine, University College London, London, UK. d.caswell@ucl.ac.uk.
⁶ German Cancer Research Center (DKFZ), Heidelberg, Germany. mirco.friedrich@dkfz-heidelberg.de.
⁷ Broad Institute of MIT and Harvard, Cambridge, MA, USA. mirco.friedrich@dkfz-heidelberg.de.
⁸ Institut de recherche en immunologie et en cancérologie (IRIC), Université de Montréal, Montreal, Quebec, Canada. carino.gurjao@umontreal.ca.
⁹ Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. liren.kong@ntu.edu.sg.
¹⁰ Cancer Science Institute, Singapore, Singapore. liren.kong@ntu.edu.sg.
¹¹ National University Cancer Institute, Singapore, Singapore. liren.kong@ntu.edu.sg.
¹² A*STAR Institute of Molecular and Cell Biology (IMCB), Singapore, Singapore. Liu_Shuang@a-star.edu.sg.
¹³ Department of Medicine, University of California, San Francisco, San Francisco, CA, USA. simone.minnie@ucsf.edu.
¹⁴ Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA. simone.minnie@ucsf.edu.
¹⁵ Princess Máxima Center, Utrecht, Netherlands. r.a.schoot-3@prinsesmaximacentrum.nl.
¹⁶ School of Pharmacy, Zhejiang University, Hangzhou, China. tangzefang@zju.edu.cn.

PMID: 41372478
DOI: 10.1038/s43018-025-01086-y

The 2025 generation

Hana Aliee et al. Nat Cancer. 2025.

. 2025 Dec 10.

doi: 10.1038/s43018-025-01086-y. Online ahead of print.

Authors

Affiliations

¹ Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK. hana.aliee@cruk.cam.ac.uk.
² Biogipuzkoa Health Research Institute, San Sebastián, Spain. leire.bejaranobosque@bio-gipuzkoa.eus.
³ Ikerbasque Basque Foundation for Science, Bilbao, Spain. leire.bejaranobosque@bio-gipuzkoa.eus.
⁴ Spanish National Cancer Research Centre (CNIO), Madrid, Spain. rcastellsg@cnio.es.
⁵ Respiratory Medicine, University College London, London, UK. d.caswell@ucl.ac.uk.
⁶ German Cancer Research Center (DKFZ), Heidelberg, Germany. mirco.friedrich@dkfz-heidelberg.de.
⁷ Broad Institute of MIT and Harvard, Cambridge, MA, USA. mirco.friedrich@dkfz-heidelberg.de.
⁸ Institut de recherche en immunologie et en cancérologie (IRIC), Université de Montréal, Montreal, Quebec, Canada. carino.gurjao@umontreal.ca.
⁹ Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore. liren.kong@ntu.edu.sg.
¹⁰ Cancer Science Institute, Singapore, Singapore. liren.kong@ntu.edu.sg.
¹¹ National University Cancer Institute, Singapore, Singapore. liren.kong@ntu.edu.sg.
¹² A*STAR Institute of Molecular and Cell Biology (IMCB), Singapore, Singapore. Liu_Shuang@a-star.edu.sg.
¹³ Department of Medicine, University of California, San Francisco, San Francisco, CA, USA. simone.minnie@ucsf.edu.
¹⁴ Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA. simone.minnie@ucsf.edu.
¹⁵ Princess Máxima Center, Utrecht, Netherlands. r.a.schoot-3@prinsesmaximacentrum.nl.
¹⁶ School of Pharmacy, Zhejiang University, Hangzhou, China. tangzefang@zju.edu.cn.

PMID: 41372478
DOI: 10.1038/s43018-025-01086-y

No abstract available

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Conflict of interest statement

Competing interests: M.J.F. is an inventor on US provisional patent application no. 63/530,465 filed by the Broad Institute and MIT relating to the work described here. M.J.F. reports speaker honoraria and consulting fees from Pfizer, Roche and Moonwalk Biosciences. The remaining authors declare no competing interests.

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The 2025 generation

Affiliations

The 2025 generation

Authors

Affiliations

Conflict of interest statement

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