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. 1978 Jan 15;34(1):21-2.
doi: 10.1007/BF01921877.

In vitro effects of melanocytolytic agents and other compounds upon dominant human melanoma tyrosinase activity

Y M Chen, W Chavin

In vitro effects of melanocytolytic agents and other compounds upon dominant human melanoma tyrosinase activity

Y M Chen et al. Experientia. .

Abstract

The activity of dominant human melanoma tyrosinase isozyme was greatly decreased by certain reducing agents. The number and geometry of phenolic groups as well as free--SH group appear important for enzymic inhibition.

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