Translating NSABP B-51 findings into practice: rethinking regional nodal irradiation in breast cancer
- PMID: 41378042
- PMCID: PMC12686210
- DOI: 10.21037/tcr-2025-1837
Translating NSABP B-51 findings into practice: rethinking regional nodal irradiation in breast cancer
Keywords: Breast cancer; HER2-positive breast cancer; neoadjuvant chemotherapy (NAC); regional nodal irradiation (RNI); triple-negative breast cancer (TNBC).
Conflict of interest statement
Conflicts of Interest: Both authors have completed the ICMJE uniform disclosure form (available at https://tcr.amegroups.com/article/view/10.21037/tcr-2025-1837/coif). The authors have no conflicts of interest to declare.
Comment on
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Omitting Regional Nodal Irradiation after Response to Neoadjuvant Chemotherapy.N Engl J Med. 2025 Jun 5;392(21):2113-2124. doi: 10.1056/NEJMoa2414859. N Engl J Med. 2025. PMID: 40466065 Free PMC article. Clinical Trial.
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- Rastogi P, O'Shaughnessy J, Martin M, et al. Adjuvant Abemaciclib Plus Endocrine Therapy for Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative, High-Risk Early Breast Cancer: Results From a Preplanned monarchE Overall Survival Interim Analysis, Including 5-Year Efficacy Outcomes. J Clin Oncol 2024;42:987-93. 10.1200/JCO.23.01994 - DOI - PMC - PubMed
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