Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2025 Dec 10;33(12):2012-2016.
doi: 10.1016/j.chom.2025.10.017.

Restoring a gut Bifidobacterium community in early infancy

Richard A Insel  1 , John B Jarman  2 , Pedro J Torres  2 , Stephen Van Dien  2 , Stephanie J Culler  2 , Willem M de Vos  3
Affiliations
Review

Restoring a gut Bifidobacterium community in early infancy

Richard A Insel et al. Cell Host Microbe. .

Abstract

An early-life microbiota with increased Bifidobacterium and human milk oligosaccharide (HMO) utilization genes has been linked to decreased risk of childhood allergic disease. As infant microbiomes increasingly have reduced Bifidobacterium, we examine early-life dysbiosis and interventions that potentially prevent or reverse this dysbiotic state, thus mitigating noncommunicable diseases.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests R.A.I. is a scientific advisor to and holds stock options in Persephone Biosciences, Inc. and holds stock options in Kenvue. J.B.J., P.J.T., S.V.D., and S.J.C are employed by Persephone Biosciences, Inc. and hold stock and/or stock options. Persephone Biosciences, Inc has filed patents related to the My Baby Biome study with all these Persephone Biosciences, Inc. co-authors named inventors on the patents. W.M.d.V. is co-founder and holds stock in Alba Health and The Akkermansia Company.

Substances

LinkOut - more resources