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. 1977 Dec;103(2):249-59.
doi: 10.1099/00221287-103-2-249.

Metabolism of 5-methyltetrahydrofolate by Lactobacillus casei

B Shane, E L Stokstad

Metabolism of 5-methyltetrahydrofolate by Lactobacillus casei

B Shane et al. J Gen Microbiol. 1977 Dec.

Abstract

The metabolism of 5-[Me-14 C]methyltetrahydrofolate in Lactobacillus casei proceeded oxidatively with incorporation of label into purine and thymidylate derivatives. No labelled methionine was formed. (l)-5-Methyltetrahydrofolate, the natural isomer, was not a substrate for the L. casei folylpoly-gamma-glutamate synthetase although the unnatural (d)-isomer was slowly metabolized to the diglutamate form.

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