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. 2026 Jan 1:200:111378.
doi: 10.1016/j.compbiomed.2025.111378. Epub 2025 Dec 12.

Transformer-based hybrid systems to combat BCI illiteracy

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Free article

Transformer-based hybrid systems to combat BCI illiteracy

Maximilian Achim Pfeffer et al. Comput Biol Med. .
Free article

Abstract

This study addresses the challenge of enhancing Brain-Computer Interfaces (BCIs), focusing on low Signal-to-Noise Ratios and "BCI illiteracy" often affecting up to 20% of users. Transformer-based models show promise but remain underexplored. Three experiments were conducted. Experiment A assessed the performance of architectures combining Convolutional and Transformer Blocks for binary Motor Imagery (MI) classification. Experiment B introduced a hybrid system, refining both block types and adding a Noise Focus Block to infuse Stochastic Noise, enhancing multi-class classification robustness. Experiment C evaluated the emerging architectures on 106 subjects, focusing on robustness across weak and strong learners. In Experiment A, the best networks achieved a validation accuracy of 0.914 and a loss of 0.146 (p=0.000967, F=12.675). In Experiment B, the proposed architecture improved multi-class MI classification to 84.5% on Dataset II, significantly improving performance for BCI-illiterate users. Experiment C showed a Kappa >83%, reduced standard deviation, and a highest validation accuracy of 88.69% across all individuals. The hybrid integration of Transformers, CNNs, and Noise-Resonance-based layers significantly enhances classification performance, particularly for weak BCI learners. Further research is recommended to optimize hybrid system architectures and hyperparameter settings to overcome current limitations in BCI performance.

Keywords: Artificial intelligence; BCI illiteracy; Biomedical engineering; Brain–computer-interface; Convolutional neural networks; Electroencephalography; Hybrid-models; Neural networks; Signal processing; Transformers.

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Conflict of interest statement

Declaration of competing interest The authors declare that there are no conflicts of interest.

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