Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1974 Dec;71(12):4723-6.
doi: 10.1073/pnas.71.12.4723.

The identification of the eukaryotic ribosomal proteins homologous with Escherichia coli proteins L7 and L12

G Stöffler, I G Wool, A Lin, K H Rak
Comparative Study

The identification of the eukaryotic ribosomal proteins homologous with Escherichia coli proteins L7 and L12

G Stöffler et al. Proc Natl Acad Sci U S A. 1974 Dec.

Abstract

Antibodies were raised against eukaryotic (rat liver) and prokaryotic (E. coli) ribosomal particles and ribosomal proteins. The antisera were characterized and used to determine the identity of the eukaryotic proteins homologous to E. coli L7 and L12. The large subunit of rat liver ribosomes contains two acidic proteins, L40 and L41; they migrate during two-dimensional polyacrylamide gel electrophoresis in a way that mimics the behavior of L7 and L12. Rat liver L40 and L41 were found to be immunologically related to E. coli L7/L12, hence the proteins are likely to share some structural homology.

PubMed Disclaimer

References

    1. Eur J Biochem. 1971 Nov 11;23(1):7-11 - PubMed
    1. Eur J Biochem. 1971 Nov 11;23(1):12-6 - PubMed
    1. J Mol Biol. 1971 Dec 14;62(2):403-5 - PubMed
    1. J Mol Biol. 1971 Dec 14;62(2):407-9 - PubMed
    1. J Biol Chem. 1972 Feb 10;247(3):805-14 - PubMed

Publication types

LinkOut - more resources