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. 2025 Nov-Dec;50(6):1021-1027.
doi: 10.4103/ijcm.ijcm_223_24. Epub 2025 May 30.

Adherence to Secondary Prevention Strategies Among Adults with Coronary Artery Disease in Rural Aluva, South India: A Community-Based Cross-Sectional Study

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Adherence to Secondary Prevention Strategies Among Adults with Coronary Artery Disease in Rural Aluva, South India: A Community-Based Cross-Sectional Study

Neeraj Vinod Mohandas et al. Indian J Community Med. 2025 Nov-Dec.

Abstract

Background: Coronary artery diseases (CADs) require chronic treatment, and recurrent coronary events can be prevented by adhering to secondary prevention guidelines. This study was conducted to determine the adherence to secondary prevention strategies and its associated factors among adults with CAD in a rural cohort in South India.

Materials and methods: A community-based cross-sectional study was conducted within the ENDIRA (Epidemiology of Non-communicable Diseases In Rural Areas) Cohort in the rural part of Aluva municipality of Ernakulam district, Kerala, India, which comprises five adjacent panchayats with a population of approximately 100,000 individuals. CAD patients aged 35 to 80 years from this cohort who have had an event of myocardial infarction in the past decade as confirmed by medical records were included. The primary outcome measured was the adherence to secondary prevention strategies across six domains as per the guidelines of the American Heart Association. A multivariable logistic regression model was used to determine the independent predictors of inadequate adherence to secondary prevention strategies.

Results: The study included 436 participants with a mean (± SD) age of 65.20 (±8.37) years, and 69% were males. The medication adherence among patients with CAD was 56.4% (95% CI 51.77-61.08), the blood pressure control was 77.3% (95% CI 73.36-81.23), the ideal body mass index was maintained by 48.9% (95% CI 44.16-53.54), the recommended physical activity was followed by 64.9% (95% CI 60.43-69.39), the smoking cessation rates were 61.8% (95% CI 52.33-71.19) and 72.5% (95% CI 68.29-76.67), and there was adequate mental health.

Conclusion: The study reveals moderate adherence among CAD patients to the secondary prevention strategies in a resource-limited setting. Ensuring community access to high-quality follow-up care after CAD is crucial.

Keywords: Adherence; coronary artery disease; prevention; preventive strategies; secondary prevention.

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Conflict of interest statement

There are no conflicts of interest.

Figures

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Figure 1
STROBE Flowchart

References

    1. McKeown RE. The epidemiologic transition: Changing patterns of mortality and population dynamics. Am J Lifestyle Med. 2009;3(1 Suppl):19S–26S. - PMC - PubMed
    1. Shu J, Jin W. Prioritizing non-communicable diseases in the post-pandemic era based on a comprehensive analysis of the GBD 2019 from 1990 to 2019. Sci Rep. 2023;13:13325. - PMC - PubMed
    1. Roth GA, Huffman MD, Moran AE, Feigin V, Mensah GA, Naghavi M, et al. Global and regional patterns in cardiovascular mortality from 1990 to 2013. Circulation. 2015;132:1667–78. - PubMed
    1. Mendis S, Abegunde D, Yusuf S, Ebrahim S, Shaper G, Ghannem H, et al. WHO study on Prevention of REcurrences of Myocardial Infarction and StrokE (WHO-PREMISE) Bull World Health Organ. 2005;83:820–9. - PMC - PubMed
    1. World Heart Federation Secondary Prevention CVD Roadmaps. Roadmap for secondary prevention of cardiovascular disease. Available from: https://world-heart-federation.org/cvd-roadmaps/whf-global-roadmaps/seco... . [Last accessed on 2024 Feb 22]

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