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. 1973 Mar;131(3):611-3.
doi: 10.1042/bj1310611.

The effect of L-ascorbate on catecholamine biosynthesis

K J Stone, B H Townsley

The effect of L-ascorbate on catecholamine biosynthesis

K J Stone et al. Biochem J. 1973 Mar.

Abstract

l-Ascorbate stimulates the enzymic hydroxylation of phenylalanine in vitro by recycling tetrahydrobiopterin, which reduces O(2) utilized in the reaction. It is suggested that ascorbate might have a similar function in vivo; this would explain the apparent regulation of tyrosine hydroxylase and tryptophan hydroxylase activities by this vitamin.

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References

    1. Biochim Biophys Acta. 1969 Nov 4;191(2):249-56 - PubMed
    1. Eur J Biochem. 1969 Jan;7(3):360-9 - PubMed
    1. J Biol Chem. 1970 Sep 25;245(18):4751-9 - PubMed
    1. J Vitaminol (Kyoto). 1970 Dec 10;16(4):276-80 - PubMed
    1. Metabolism. 1971 Mar;20(3):247-54 - PubMed