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. 2026 Jan 3.
doi: 10.1038/s41598-025-34496-0. Online ahead of print.

Lycopene ameliorates intestinal barrier dysfunction following traumatic brain injury by inhibiting pyroptosis

Hongling Zhang  1   2 , Qiang Liu  3 , Jinshan Peng  3 , Xizhe Chen  3 , Mouying Liu  3 , Yun Chen  3 , Sican Wei  2 , Minglian Huang  2 , Ling Huang  2 , Yanjun Liao  2 , Weiwen Chen  2 , Tianlai Lin  4 , Xiaodan Wu  5
Affiliations
Free article

Lycopene ameliorates intestinal barrier dysfunction following traumatic brain injury by inhibiting pyroptosis

Hongling Zhang et al. Sci Rep. .
Free article
No abstract available

Keywords: Intestinal barrier function; Lycopene; Pyroptosis; Traumatic brain injury.

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Conflict of interest statement

Declarations. Competing interests: The authors declare no competing interests. Informed consent: All authors provided consent to the publication of this manuscript. Participants provided consent for the publication of anonymized data collected from the study. Ethical approval and consent to participate: The animal experiment was reported in accordance with the ARRIVE guidelines and was approved by the Experimental Animal Ethics Committee of Quanzhou Medical College (No. 2024065). All methods were performed in accordance with the relevant guidelines and regulations. The clinical trial adhered strictly to the CONSORT guidelines and the principles of the Declaration of Helsinki, received approval from the Ethics Committee of Quanzhou First Hospital Affiliated to Fujian Medical University (No. QYL [2023] K056) and was first registered in the China Medical Research Registration and Filing Information System on 28/03/2024 (Registration Number: MR-35-24-017311).

References

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