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. 1974 Jan;71(1):225-9.
doi: 10.1073/pnas.71.1.225.

Activation of transcription of hut DNA by glutamine synthetase

B Tyler, A B Deleo, B Magasanik

Activation of transcription of hut DNA by glutamine synthetase

B Tyler et al. Proc Natl Acad Sci U S A. 1974 Jan.

Abstract

The correct transcription of the hut (histidine utilization) operon DNA of Salmonella typhimurium requires activation either by 3':5'-cyclic adenosine monophosphate and catabolite-activating protein or by nonadenylylated glutamine synthetase (EC 6.3.1.2.). Thus, glutamine synthetase plays a regulatory role distinct from its enzymatic function.

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References

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