Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Jan;19(1):107-15.
doi: 10.1128/iai.19.1.107-115.1978.

Specificity of salivary-bacterial interactions: role of terminal sialic acid residues in the interaction of salivary glycoproteins with Streptococcus sanguis and Streptococcus mutans

M J Levine, M C Herzberg, M S Levine, S A Ellison, M W Stinson, H C Li, T van Dyke

Specificity of salivary-bacterial interactions: role of terminal sialic acid residues in the interaction of salivary glycoproteins with Streptococcus sanguis and Streptococcus mutans

M J Levine et al. Infect Immun. 1978 Jan.

Abstract

Four highly purified salivary glycoproteins were used to study salivary-bacterial interactions. One pair of glycoproteins was mucin-like in composition, whereas the second pair was not. By an agglutination assay, it was found that only the mucin-glycoproteins agglutinated Streptococcus sanguis and S. mutans. Removal of sialic acid from these molecules resulted in a loss of agglutination of S. sanguis but not of S. mutans. The agglutination phenomenon was shown to require a salivary macromolecule of at least 150,000 daltons.

PubMed Disclaimer

References

    1. Biochem J. 1960 Jun;75:435-40 - PubMed
    1. Biochem J. 1961 Dec;81:639-47 - PubMed
    1. J Biol Chem. 1959 Aug;234(8):1971-5 - PubMed
    1. Nature. 1958 Apr 19;181(4616):1154-5 - PubMed
    1. J Biol Chem. 1955 Jan;212(1):335-43 - PubMed

Publication types

LinkOut - more resources