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. 1978 Feb;133(2):472-6.
doi: 10.1128/jb.133.2.472-476.1978.

Effect of cerulenin on Streptococcus faecalis macromolecular synthesis and cell division

D Carson, L Daneo-Moore

Effect of cerulenin on Streptococcus faecalis macromolecular synthesis and cell division

D Carson et al. J Bacteriol. 1978 Feb.

Abstract

The antibiotic cerulenin has been used to study macromolecular synthesis and cell division in Streptococcus faecalis. The data suggest that lipid and lipoteichoic acid synthesis as well as cell number increase are affected prior to any observable effects on overall mass increase or DNA, RNA, protein, or peptidoglycan synthesis. Treatment with cerulenin of cultures growing at various rates and analysis of the subsequent cell divisions indicate that the antibiotic may block a cell cycle event that precedes the completion of chromosome replication by about 10 min.

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References

    1. J Lipid Res. 1973 May;14(3):370-2 - PubMed
    1. Infect Immun. 1976 Nov;14(5):1241-52 - PubMed
    1. Biochem Biophys Res Commun. 1973 Jan 23;50(2):200-10 - PubMed
    1. Biochem J. 1969 Dec;115(4):697-701 - PubMed
    1. J Bacteriol. 1974 May;118(2):681-92 - PubMed

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