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Comparative Study
. 1979 Aug 15;182(2):625-8.
doi: 10.1042/bj1820625.

Comparison of superoxide with other reducing agents in the biological production of hydroxyl radicals

C C Winterbourn
Comparative Study

Comparison of superoxide with other reducing agents in the biological production of hydroxyl radicals

C C Winterbourn. Biochem J. .

Abstract

Iron--EDTA was shown to catalyse OH. production from H2O2 and ascorbate by a mechanism largely independent of superoxide. When ascorbate and superoxide were both present, the ascorbate mechanism was more important than superoxide as a source of OH., and would appear to be more significantly biologically.

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References

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