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. 2026 Jan 12.
doi: 10.2215/CJN.0000001001. Online ahead of print.

Medication Dosing in Online Hemodiafiltration: Clinical Considerations

Stefano Stuard  1 , Dinesh K Chatoth  2 , Kyle Tonnies  2 , Chance Mysayphonh  2 , Michael S Anger  2
Affiliations

Medication Dosing in Online Hemodiafiltration: Clinical Considerations

Stefano Stuard et al. Clin J Am Soc Nephrol. .
No abstract available

Keywords: ESKD; hemodialysis; pharmacokinetics; pharmacology.

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References

    1. Grooteman MP, van den Dorpel MA, Bots ML, et al. Effect of online hemodiafiltration on all-cause mortality and cardiovascular outcomes. J Am Soc Nephrol. 2012;23(6):1087–1096. doi: 10.1681/ASN.2011121140 - DOI
    1. Ok E, Asci G, Toz H, et al. Mortality and cardiovascular events in online haemodiafiltration (OL-HDF) compared with high-flux dialysis: results from the Turkish OL-HDF study. Nephrol Dial Transplant. 2013;28(1):192–202. doi: 10.1093/ndt/gfs407 - DOI
    1. Maduell F, Moreso F, Pons M, et al. High-efficiency postdilution online hemodiafiltration reduces all-cause mortality in hemodialysis patients. J Am Soc Nephrol. 2013;24(3):487–497. doi: 10.1681/ASN.2012080875 - DOI
    1. Blankestijn PJ, Vernooij RWM, Hockham C, et al. Effect of hemodiafiltration or hemodialysis on mortality in kidney failure. N Engl J Med. 2023;389(8):700–709. doi: 10.1056/NEJMoa2304820 - DOI
    1. Vernooij RWM, Hockham C, Strippoli G, et al. Haemodiafiltration versus haemodialysis for kidney failure: an individual patient data meta-analysis of randomised controlled trials. Lancet. 2024;404(10464):1742–1749. doi: 10.1016/S0140-6736(24)01859-2 - DOI

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