doi: 10.1126/science.186.4165.738.
Gamma-aminobutyric acid effects on pituitary gonadotropin secretion
- PMID: 4153578
- DOI: 10.1126/science.186.4165.738
Item in Clipboard
Gamma-aminobutyric acid effects on pituitary gonadotropin secretion
Science.
.
Abstract
Gamma-aminobutyric acid (GABA) injected into the third ventricle of male rats promotes the release of pituitary luteinizing hormone (LH) but not follicle-stimulating hormone. When GABA was injected directly into the pituitary it was ineffective in promoting LH release. This evidence suggests that GABA may play a role in controlling the discharge of hypothalamic luteinizing hormone releasing factor.
Similar articles
-
The effects of gamma-aminobutyric acid on prolactin and gonadotropin secretion in the unanesthetized rat.Endocrinology. 1977 May;100(5):1437-42. doi: 10.1210/endo-100-5-1437. Endocrinology. 1977. PMID: 849735
-
Acute modulation of pituitary gonadotrophin secretion by oestradiol or testosterone in healthy men.J Endocrinol. 1974 Oct;63(1):251-2. doi: 10.1677/joe.0.0630251. J Endocrinol. 1974. PMID: 4607865 No abstract available.
-
Obtention of antisera against a hypothalamic decapeptide (luteinizing hormone-follicle stimulating hormone releasing hormone) which stimulated the release of pituitary gonadotropins and development of its radioimmunoassay.Biochim Biophys Acta. 1973 Feb 28;297(2):540-8. doi: 10.1016/0304-4165(73)90101-3. Biochim Biophys Acta. 1973. PMID: 4574551 No abstract available.
-
Hypothalamic control of FSH and LH by FSH-RF, LHRH, cytokines, leptin and nitric oxide.Neuroimmunomodulation. 1998 May-Aug;5(3-4):193-202. doi: 10.1159/000026337. Neuroimmunomodulation. 1998. PMID: 9730686 Review.
-
FSH-releasing hormone and LH-releasing hormone.Vitam Horm. 1972;30:83-164. doi: 10.1016/s0083-6729(08)60795-5. Vitam Horm. 1972. PMID: 4565623 Review. No abstract available.
Cited by
-
GABA(B) receptors in neuroendocrine regulation.Cell Mol Neurobiol. 2008 Sep;28(6):803-17. doi: 10.1007/s10571-008-9263-4. Epub 2008 Feb 9. Cell Mol Neurobiol. 2008. PMID: 18264754 Free PMC article. Review.
-
Deciphering the Contributions of CRH Receptors in the Brain and Pituitary to Stress-Induced Inhibition of the Reproductive Axis.Front Mol Neurosci. 2018 Aug 30;11:305. doi: 10.3389/fnmol.2018.00305. eCollection 2018. Front Mol Neurosci. 2018. PMID: 30214395 Free PMC article.
-
Involvement of preoptic-anterior hypothalamic GABA neurons in the regulation of pituitary LH and prolactin release.Exp Brain Res. 1983;52(3):356-62. doi: 10.1007/BF00238029. Exp Brain Res. 1983. PMID: 6653697
-
Inhibitory actions of amino acids in the preoptic-anterior hypothalamus of the rat.Exp Brain Res. 1981;43(2):154-8. doi: 10.1007/BF00237759. Exp Brain Res. 1981. PMID: 6265264
-
Depolarising and hyperpolarising actions of GABA(A) receptor activation on gonadotrophin-releasing hormone neurones: towards an emerging consensus.J Neuroendocrinol. 2011 Jul;23(7):557-69. doi: 10.1111/j.1365-2826.2011.02145.x. J Neuroendocrinol. 2011. PMID: 21518033 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
