Review
doi: 10.1016/j.chest.2025.12.043.
Online ahead of print.
Shaping the Future of Respiratory Care: A look into the next decade and strategic recommendations by EUFOREA
X Bertels
1
, Gk Scadding
2
, V Backer
3
, S Lau
4
, Fokkens Wj
5
, Pj Barnes
6
, M Bernal Sprekelsen
7
, L Bjermer
8
, M Blaiss
9
, E Borzova
10
, Mc Brüggen
11
, Gg Brusselle
12
, L Cardell
13
, Dm Conti
14
, M Cornet
15
, E De Corso
16
, B De Groeve
17
, R Djukanovic
18
, At Fox
19
, M Gaga
20
, P Gevaert
21
, P Gibson
22
, C Gray
23
, J Han
24
, L Heaney
25
, E Heffler
26
, Hj Hoffmann
27
, C Hopkins
28
, D Jackson
29
, O Jauhola
30
, M Jesenak
31
, P Johansen
32
, E Khaleva
33
, B Landis
34
, S Lee
35
, V Lund
36
, M Mäkelä
37
, M McDonald
38
, E Melén
39
, J Mullol
40
, A Nieto-García
41
, I Pavord
42
, A Peters
43
, D Price
44
, S Quirce
45
, D Ryan
46
, P Sahlstrand-Johnson
47
, S Scheire
21
, P Schmid-Grendelmeier
48
, S Schneider
49
, B Senior
50
, Cme Shire
51
, P Smith
52
, Z Szepfalusi
53
, Mta Teeling
51
, Me Wechsler
54
, P Houssiau
55
, Kf Rabe
56
, Pw Hellings
57
, Jl Castro
58
Affiliations
Affiliations
- 1 The European Forum for Research and Education in Allergy and Airway Diseases, Brussels, Belgium. Upper Airways Research Laboratory, Department of Head and Skin, Ghent University, Ghent, Belgium. Electronic address: xander.bertels@euforea.org.
- 2 ENT Department, Royal National ENT Hospital, London, United Kingdom. Division of Immunity and Infection, University College, London, United Kingdom.
- 3 Department of Otorhinolaryngology, Head & Neck Surgery, and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark.
- 4 Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
- 5 Amsterdam UMC, University of Amsterdam, Department of Otorhinolarynogology, Amsterdam, the Netherlands.
- 6 National Heart and Lung Institute, Imperial College London, London, United Kingdom.
- 7 Hospital Clinic, Barcelona, University of Barcelona, Spain.
- 8 Department of Respiratory Medicine & Allergology, Institute for Clinical Science, Skane University Hospital, Lund University, Lund, Sweden.
- 9 Medical College of Georgia at Augusta University, Augusta, GA, United States.
- 10 Dermatology Division, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
- 11 Christine Kühne-Center for Allergy Research and Education (CK-CARE), Davos, Switzerland. Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.
- 12 Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium, Departments of Epidemiology and Respiratory Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands.
- 13 Division of ENT Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden. Department of ENT Diseases, Karolinska University Hospital, Stockholm, Sweden.
- 14 Escuela de Doctorado UAM, Centro de Estudios de Posgrado, Universidad Autónoma de Madrid, Madrid, Spain. Allergy and Clinical Immunology Research Unit, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.
- 15 Department of Otorhinolaryngology, Alrijne Hospital, Leiden, the Netherlands.
- 16 UOC Otorinolaringoiatria, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
- 17 imec, Leuven, Belgium.
- 18 School of Clinical and Experimental Sciences, Medical Faculty, University of Southampton and NIHR Southampton Biomedical Research Centre, Southampton, United Kingdom.
- 19 Children's Allergy Service, Evelina London Children's Hospital, London, United Kingdom. Department of Paediatric Allergy, King's College London, London, United Kingdom.
- 20 1st Respiratory Medicine Department, Hygeia Hospital, Marousi, Greece.
- 21 Upper Airways Research Laboratory, Department of Head and Skin, Ghent University, Ghent, Belgium.
- 22 Dept of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, Australia.
- 23 Department of Paediatrics, University of Cape Town, Cape Town, South Africa.
- 24 Department of Otolaryngology & Head and Neck Surgery, Eastern Virginia Medical School, Norfolk, VA, USA.
- 25 Wellcome-Wolfson Institute for Experimental Medicine, Queens University Belfast, Belfast, United Kingdom.
- 26 Personalized Medicine Asthma and Allergy Unit - IRCCS Humanitas Research Hospital, Rozzano (Milan), Italy // Department of Biomedical Sciences - Humanitas University, Pieve Emanuele (Milan), Italy.
- 27 Department of Clinical Medicine, University of Aarhus, Aarhus, Denmark.
- 28 King's College London, London, United Kingdom.
- 29 Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wis, USA.
- 30 HUS Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland.
- 31 Institute of Clinical Immunology and Medical Genetics, Department of Pulmonology and Phthisiology, Department of Pediatrics and Adolescent Medicine, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Hospital in Martin, Martin, Slovakia; Department of Clinical Immunology and Allergology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Hospital in Martin, Martin, Slovakia.
- 32 Department of Dermatology, University of Zurich, Zurich, Switzerland. Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland.
- 33 Clinical and Experimental Sciences and Human Development in Health, Faculty of Medicine, University of Southampton, UK.
- 34 Unité de Rhinologie-Olfactologie, Service d'Oto-Rhino-Laryngologie et de Chirurgie cervico-faciale, Hôpitaux Universitaires de Genève, Geneve, Switzerland.
- 35 Division of Otolaryngology - Head & Neck Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
- 36 Ear Institute, University College London, London, United Kingdom. Royal National Ear, Nose, Throat and Eastman Dental Hospital, UCLH, London, United Kingdom.
- 37 Skin and Allergy Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
- 38 The Allergy Clinic, Johannesburg, South Africa.
- 39 Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet and Sachs' Children and Youth Hospital, Stockholm, Sweden.
- 40 Rhinology Unit and Smell Clinic, ENT Department, Hospital Clínic Barcelona, IDIBAPS, Universitat de Barcelona, CIBERES. Barcelona, Catalonia, Spain.
- 41 Pediatric Pulmonology & Allergy Unit, Health Research Institute, La Fe University Hospital, Valencia, Spain.
- 42 Respiratory Medicine Unit and Oxford Respiratory NIHR BRC, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
- 43 Department of Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
- 44 Observational and Pragmatic Research Institute, Singapore, Singapore. Centre of Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom.
- 45 Department of Allergy, La Paz University Hospital, IdiPAZ, Madrid, Spain.
- 46 Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
- 47 Skåne University Hospital, Dep of Otorhinolaryngology, 221 85 Lund, Sweden.
- 48 Allergy Unit, Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland, Department of Dermatology, High Altitude Clinic, Medicine Campus Davos-Wolfgang, Davos-Wolfgang, Switzerland.
- 49 Department of Otorhinolaryngology - Head & Neck Surgery, Medical University of Vienna, Austria.
- 50 Harold C Pillsbury, III Distinguished Professor of Otolaryngology, Chief, Division of Rhinology, Allergy, and Endoscopic Skull Base Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
- 51 Patient Advisory Board, The European Forum for Research and Education in Allergy and Airway Diseases, Brussels, Belgium.
- 52 School of Medicine, Griffith University, Gold Coast, QLD, Australia. Menzies Centre, National Centre for NeuroImmunology and Emerging Disease, Gold Coast, QLD, Australia.
- 53 Department of Pediatrics and Adolescent Medicine, Division of Pediatric Pulmonology, Allergology and Endocrinology, Comprehensive Center Pediatrics, Medical University of Vienna, Vienna, Austria.
- 54 Department of Medicine, National Jewish Health, Denver, CO, USA.
- 55 Novo Holdings, Denmark.
- 56 LungenClinic Grosshansdorf (member of the German Center for Lung Research [DZL]), Airway Research Center North (ARCN), Grosshansdorf, Germany. Christian-Albrechts University, DZL, ARCN, Kiel, Germany.
- 57 Department of Microbiology and Immunology, Allergy and Clinical Immunology Research Unit, KU Leuven, Leuven, Belgium. Clinical Department of Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium.
- 58 World Health Organization, Genèva, Switzerland.
- PMID: 41544956
- DOI: 10.1016/j.chest.2025.12.043
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Review
Shaping the Future of Respiratory Care: A look into the next decade and strategic recommendations by EUFOREA
X Bertels et al.
Chest.
.
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doi: 10.1016/j.chest.2025.12.043.
Online ahead of print.
Authors
X Bertels
1
, Gk Scadding
2
, V Backer
3
, S Lau
4
, Fokkens Wj
5
, Pj Barnes
6
, M Bernal Sprekelsen
7
, L Bjermer
8
, M Blaiss
9
, E Borzova
10
, Mc Brüggen
11
, Gg Brusselle
12
, L Cardell
13
, Dm Conti
14
, M Cornet
15
, E De Corso
16
, B De Groeve
17
, R Djukanovic
18
, At Fox
19
, M Gaga
20
, P Gevaert
21
, P Gibson
22
, C Gray
23
, J Han
24
, L Heaney
25
, E Heffler
26
, Hj Hoffmann
27
, C Hopkins
28
, D Jackson
29
, O Jauhola
30
, M Jesenak
31
, P Johansen
32
, E Khaleva
33
, B Landis
34
, S Lee
35
, V Lund
36
, M Mäkelä
37
, M McDonald
38
, E Melén
39
, J Mullol
40
, A Nieto-García
41
, I Pavord
42
, A Peters
43
, D Price
44
, S Quirce
45
, D Ryan
46
, P Sahlstrand-Johnson
47
, S Scheire
21
, P Schmid-Grendelmeier
48
, S Schneider
49
, B Senior
50
, Cme Shire
51
, P Smith
52
, Z Szepfalusi
53
, Mta Teeling
51
, Me Wechsler
54
, P Houssiau
55
, Kf Rabe
56
, Pw Hellings
57
, Jl Castro
58
Affiliations
- 1 The European Forum for Research and Education in Allergy and Airway Diseases, Brussels, Belgium. Upper Airways Research Laboratory, Department of Head and Skin, Ghent University, Ghent, Belgium. Electronic address: xander.bertels@euforea.org.
- 2 ENT Department, Royal National ENT Hospital, London, United Kingdom. Division of Immunity and Infection, University College, London, United Kingdom.
- 3 Department of Otorhinolaryngology, Head & Neck Surgery, and Audiology, Rigshospitalet, Copenhagen University, Copenhagen, Denmark.
- 4 Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité Universitätsmedizin Berlin, Berlin, Germany.
- 5 Amsterdam UMC, University of Amsterdam, Department of Otorhinolarynogology, Amsterdam, the Netherlands.
- 6 National Heart and Lung Institute, Imperial College London, London, United Kingdom.
- 7 Hospital Clinic, Barcelona, University of Barcelona, Spain.
- 8 Department of Respiratory Medicine & Allergology, Institute for Clinical Science, Skane University Hospital, Lund University, Lund, Sweden.
- 9 Medical College of Georgia at Augusta University, Augusta, GA, United States.
- 10 Dermatology Division, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
- 11 Christine Kühne-Center for Allergy Research and Education (CK-CARE), Davos, Switzerland. Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.
- 12 Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium, Departments of Epidemiology and Respiratory Medicine, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands.
- 13 Division of ENT Diseases, Department of Clinical Sciences, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden. Department of ENT Diseases, Karolinska University Hospital, Stockholm, Sweden.
- 14 Escuela de Doctorado UAM, Centro de Estudios de Posgrado, Universidad Autónoma de Madrid, Madrid, Spain. Allergy and Clinical Immunology Research Unit, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.
- 15 Department of Otorhinolaryngology, Alrijne Hospital, Leiden, the Netherlands.
- 16 UOC Otorinolaringoiatria, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
- 17 imec, Leuven, Belgium.
- 18 School of Clinical and Experimental Sciences, Medical Faculty, University of Southampton and NIHR Southampton Biomedical Research Centre, Southampton, United Kingdom.
- 19 Children's Allergy Service, Evelina London Children's Hospital, London, United Kingdom. Department of Paediatric Allergy, King's College London, London, United Kingdom.
- 20 1st Respiratory Medicine Department, Hygeia Hospital, Marousi, Greece.
- 21 Upper Airways Research Laboratory, Department of Head and Skin, Ghent University, Ghent, Belgium.
- 22 Dept of Respiratory and Sleep Medicine, John Hunter Hospital, Newcastle, Australia.
- 23 Department of Paediatrics, University of Cape Town, Cape Town, South Africa.
- 24 Department of Otolaryngology & Head and Neck Surgery, Eastern Virginia Medical School, Norfolk, VA, USA.
- 25 Wellcome-Wolfson Institute for Experimental Medicine, Queens University Belfast, Belfast, United Kingdom.
- 26 Personalized Medicine Asthma and Allergy Unit - IRCCS Humanitas Research Hospital, Rozzano (Milan), Italy // Department of Biomedical Sciences - Humanitas University, Pieve Emanuele (Milan), Italy.
- 27 Department of Clinical Medicine, University of Aarhus, Aarhus, Denmark.
- 28 King's College London, London, United Kingdom.
- 29 Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wis, USA.
- 30 HUS Skin and Allergy Hospital, Helsinki University Hospital, Helsinki, Finland.
- 31 Institute of Clinical Immunology and Medical Genetics, Department of Pulmonology and Phthisiology, Department of Pediatrics and Adolescent Medicine, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Hospital in Martin, Martin, Slovakia; Department of Clinical Immunology and Allergology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, University Hospital in Martin, Martin, Slovakia.
- 32 Department of Dermatology, University of Zurich, Zurich, Switzerland. Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland.
- 33 Clinical and Experimental Sciences and Human Development in Health, Faculty of Medicine, University of Southampton, UK.
- 34 Unité de Rhinologie-Olfactologie, Service d'Oto-Rhino-Laryngologie et de Chirurgie cervico-faciale, Hôpitaux Universitaires de Genève, Geneve, Switzerland.
- 35 Division of Otolaryngology - Head & Neck Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
- 36 Ear Institute, University College London, London, United Kingdom. Royal National Ear, Nose, Throat and Eastman Dental Hospital, UCLH, London, United Kingdom.
- 37 Skin and Allergy Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
- 38 The Allergy Clinic, Johannesburg, South Africa.
- 39 Department of Clinical Science and Education Södersjukhuset, Karolinska Institutet and Sachs' Children and Youth Hospital, Stockholm, Sweden.
- 40 Rhinology Unit and Smell Clinic, ENT Department, Hospital Clínic Barcelona, IDIBAPS, Universitat de Barcelona, CIBERES. Barcelona, Catalonia, Spain.
- 41 Pediatric Pulmonology & Allergy Unit, Health Research Institute, La Fe University Hospital, Valencia, Spain.
- 42 Respiratory Medicine Unit and Oxford Respiratory NIHR BRC, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.
- 43 Department of Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
- 44 Observational and Pragmatic Research Institute, Singapore, Singapore. Centre of Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom.
- 45 Department of Allergy, La Paz University Hospital, IdiPAZ, Madrid, Spain.
- 46 Usher Institute, University of Edinburgh, Edinburgh, United Kingdom.
- 47 Skåne University Hospital, Dep of Otorhinolaryngology, 221 85 Lund, Sweden.
- 48 Allergy Unit, Department of Dermatology, University Hospital of Zurich, Zurich, Switzerland, Department of Dermatology, High Altitude Clinic, Medicine Campus Davos-Wolfgang, Davos-Wolfgang, Switzerland.
- 49 Department of Otorhinolaryngology - Head & Neck Surgery, Medical University of Vienna, Austria.
- 50 Harold C Pillsbury, III Distinguished Professor of Otolaryngology, Chief, Division of Rhinology, Allergy, and Endoscopic Skull Base Surgery, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
- 51 Patient Advisory Board, The European Forum for Research and Education in Allergy and Airway Diseases, Brussels, Belgium.
- 52 School of Medicine, Griffith University, Gold Coast, QLD, Australia. Menzies Centre, National Centre for NeuroImmunology and Emerging Disease, Gold Coast, QLD, Australia.
- 53 Department of Pediatrics and Adolescent Medicine, Division of Pediatric Pulmonology, Allergology and Endocrinology, Comprehensive Center Pediatrics, Medical University of Vienna, Vienna, Austria.
- 54 Department of Medicine, National Jewish Health, Denver, CO, USA.
- 55 Novo Holdings, Denmark.
- 56 LungenClinic Grosshansdorf (member of the German Center for Lung Research [DZL]), Airway Research Center North (ARCN), Grosshansdorf, Germany. Christian-Albrechts University, DZL, ARCN, Kiel, Germany.
- 57 Department of Microbiology and Immunology, Allergy and Clinical Immunology Research Unit, KU Leuven, Leuven, Belgium. Clinical Department of Otorhinolaryngology, Head and Neck Surgery, University Hospitals Leuven, Leuven, Belgium.
- 58 World Health Organization, Genèva, Switzerland.
- PMID: 41544956
- DOI: 10.1016/j.chest.2025.12.043
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Abstract
Chronic respiratory diseases (CRDs) remain one of the leading causes of preventable morbidity and disability worldwide, and affect up to one-third of the total Western population in 2025. Recognising the substantial burden of inflammatory airway diseases such as asthma, chronic obstructive pulmonary disease (COPD), chronic rhinosinusitis (CRS) and respiratory allergy, the European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) organised the symposium "Shaping the Future of Respiratory Care" in April 2025 in Brussels, Belgium at the occasion of the 10 year jubilee. Featuring keynote speakers from the World Health Organization (WHO) and EUFOREA, this initiative had the following aims: (i) promoting dialogue on translating innovations into daily clinical practice, (ii) encouraging collaboration between the different stakeholders in the respiratory field, and (iii) defining strategic priorities to transform respiratory care and arrest the CRD epidemic over the next decade. The symposium highlighted the importance of moving towards predictive, preventive, and patient-centred medicine, while supporting value-based healthcare systems to improve long-term patient outcomes. This report summarises the main insights and strategic directions discussed at the meeting.
Keywords: Action Plan; Chronic Respiratory Diseases; EUFOREA; Global Health; Respiratory Care.
Copyright © 2026. Published by Elsevier Inc.
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