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Comparative Study
. 1974 Sep;52(1):101-3.
doi: 10.1111/j.1476-5381.1974.tb09693.x.

Antagonism of inhibitory amino acid action by tubocurarine

D R Curtis, C J Game, R M McCulloch
Comparative Study

Antagonism of inhibitory amino acid action by tubocurarine

D R Curtis et al. Br J Pharmacol. 1974 Sep.

Abstract

A comparison has been made of the antagonism by microelectrophoretically administered (+)-tubocurarine, bicuculline methochloride and strychnine of the inhibition of spinal interneurones and Renshaw cells in the cat by glycine and gamma-aminobutyric acid. The results indicate that (+)-tubocurarine would be of little use in assessing which of these amino acids was the transmitter at central inhibitory synapses.

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References

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    1. Brain Res. 1971 Oct 8;33(1):57-73 - PubMed
    1. Nat New Biol. 1972 Dec 13;240(102):219-20 - PubMed
    1. Nature. 1972 Nov 3;240(5375):51-2 - PubMed
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