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Case Reports
. 2026 Jan 16;105(3):e45726.
doi: 10.1097/MD.0000000000045726.

Simultaneous transcatheter aortic and mitral valve-in-valve replacement: A case report

Yue Mao  1 , Yang Zhan, Rong Li, Jingjing Chen, Quanfeng Mo
Affiliations
Case Reports

Simultaneous transcatheter aortic and mitral valve-in-valve replacement: A case report

Yue Mao et al. Medicine (Baltimore). .

Abstract

Rationale: There are fewer reports in China about re-performing combined transcatheter transcatheter aortic and mitral valve-in-valve replacement after bioprosthetic valve failure. Due to the higher difficulty of the combined secondary bivalve procedure and the greater risk of pericardial tamponade and malignant arrhythmias, the professional demands on the surgeon and team are extremely high. It is particularly important to provide quality perioperative care for such patients.

Patient concerns: This study reports a case of bioprosthetic valve failure after undergoing transcatheter aortic and mitral bicuspid valve-in-valve replacement.After active treatment and careful care, the patient recovered well after the operation and had a good quality of life during the 1 year follow-up period.

Diagnoses: Valve function was measured by 3-dimensional echocardiography.

Interventions: The key points of perioperative care include: close monitoring of the patient's condition and provision of first aid before surgery; close monitoring of hemodynamic parameters, management of fluid balance, provision of respiratory support and oxygen therapy management, prevention of complications and early cardiac rehabilitation after surgery.

Outcomes: On the 16th day after the operation, the 3-dimensional echocardiogram showed that the mitral regurgitation was slight. Mitral regurgitation was slight, and aortic valve flow velocity and differential pressure were normalized. At 1 year follow-up, there were no adverse cardiovascular events and quality of life improved.

Lessons: For patients undergoing simultaneous transcatheter bivalve replacement with multiple comorbidities, focus should be placed on constructing an integrated perioperative intervention pathway to comprehensively improve clinical tolerance and control the risk of complex cases.

Keywords: case report; transcatheter aortic valve replacement; transcatheter mitral valve replacement; valve-in-valve.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

References

    1. Zhang HB, Pan XB, Guo YQ, et al. Multicenter expert recommendations on interventional valve-in-valve technology for mitral bioprosthetic valve destruction in China. Chin J Clin Thorac Cardiovasc Surg. 2024;31:1090–5.
    1. Mohty D, Orszulak TA, Schaff HV, Avierinos JF, Tajik JA, Enriquez-Sarano M. Very long-term survival and durability of mitral valve repair for mitral valve prolapse. Circulation. 2001;104:I1–7. - PubMed
    1. Jiang HB, Zong GJ, Huang XM, Bai Y, Chen Y, Zhao XX. Experimental study of transcatheter aortic valve replacement by “valve-in-valve” fashion with domestic nitinol prosthesis stents. Chin J Interv Cardiol. 2013;21:235–9.
    1. Fatehi HA, Turcotte M, Dennehy C, Kim A, Malaisrie SC, Kent W. Contemporary reoperative mitral valve surgery: technical considerations and clinical outcomes. Innovations (Phila). 2020;15:425–39. - PubMed
    1. Mehaffey HJ, Hawkins RB, Schubert S, et al. Contemporary outcomes in reoperative mitral valve surgery. Heart. 2018;104:652–6. - PubMed

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