Retraction Note: SUMOylation of VEGFR2 regulates its intracellular trafficking and pathological angiogenesis

Huanjiao Jenny Zhou^#¹, Zhe Xu^#^{2

3}, Zongren Wang^#^{2

4}, Haifeng Zhang², Zhen W Zhuang⁵, Michael Simons⁵, Wang Min^{6

7}

Affiliations

¹ Interdepartmental Program in Vascular Biology and Therapeutics, Department of Pathology, Yale University School of Medicine, 10 Amistad St., New Haven, CT, 06520, USA. huanjiao.zhou@yale.edu.
² Interdepartmental Program in Vascular Biology and Therapeutics, Department of Pathology, Yale University School of Medicine, 10 Amistad St., New Haven, CT, 06520, USA.
³ Department of Ophthalmology, First Affiliated Hospital of Jinan University, Guangzhou, 510630, Guangdong Province, P. R. China.
⁴ The First Affiliated Hospital, Sun Yat-sen University, Zhongshan Road II, Guangzhou, 510080, P. R. China.
⁵ Section of Cardiology, Department of Internal Medicine, Yale University School of Medicine, 10 Amistad St., New Haven, CT, 06520, USA.
⁶ Interdepartmental Program in Vascular Biology and Therapeutics, Department of Pathology, Yale University School of Medicine, 10 Amistad St., New Haven, CT, 06520, USA. wang.min@yale.edu.
⁷ The First Affiliated Hospital, Sun Yat-sen University, Zhongshan Road II, Guangzhou, 510080, P. R. China. wang.min@yale.edu.

^# Contributed equally.

Huanjiao Jenny Zhou et al. Nat Commun. 2026.

. 2026 Jan 21;17(1):769.

doi: 10.1038/s41467-025-68233-y.

Huanjiao Jenny Zhou^#¹, Zhe Xu^#^{2

3}, Zongren Wang^#^{2

4}, Haifeng Zhang², Zhen W Zhuang⁵, Michael Simons⁵, Wang Min^{6

7}

¹ Interdepartmental Program in Vascular Biology and Therapeutics, Department of Pathology, Yale University School of Medicine, 10 Amistad St., New Haven, CT, 06520, USA. huanjiao.zhou@yale.edu.
² Interdepartmental Program in Vascular Biology and Therapeutics, Department of Pathology, Yale University School of Medicine, 10 Amistad St., New Haven, CT, 06520, USA.
³ Department of Ophthalmology, First Affiliated Hospital of Jinan University, Guangzhou, 510630, Guangdong Province, P. R. China.
⁴ The First Affiliated Hospital, Sun Yat-sen University, Zhongshan Road II, Guangzhou, 510080, P. R. China.
⁵ Section of Cardiology, Department of Internal Medicine, Yale University School of Medicine, 10 Amistad St., New Haven, CT, 06520, USA.
⁶ Interdepartmental Program in Vascular Biology and Therapeutics, Department of Pathology, Yale University School of Medicine, 10 Amistad St., New Haven, CT, 06520, USA. wang.min@yale.edu.
⁷ The First Affiliated Hospital, Sun Yat-sen University, Zhongshan Road II, Guangzhou, 510080, P. R. China. wang.min@yale.edu.

^# Contributed equally.

No abstract available

Retraction of

SUMOylation of VEGFR2 regulates its intracellular trafficking and pathological angiogenesis.
Zhou HJ, Xu Z, Wang Z, Zhang H, Zhuang ZW, Simons M, Min W. Zhou HJ, et al. Nat Commun. 2018 Aug 17;9(1):3303. doi: 10.1038/s41467-018-05812-2. Nat Commun. 2018. Retraction in: Nat Commun. 2026 Jan 21;17(1):769. doi: 10.1038/s41467-025-68233-y. PMID: 30120232 Free PMC article. Retracted.

1. Zhang, H. et al. AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice. J Clin. Invest. 118, 3904–3916 (2008). - PMC - PubMed