Purification and properties of cyclic AMP dependent and independent protein kinases from rat pancreas
- PMID: 4157
- DOI: 10.1016/s0300-9084(75)80208-2
Purification and properties of cyclic AMP dependent and independent protein kinases from rat pancreas
Abstract
Three protein kinases Ko, K1, and KII have been extracted from rat pancreas homogenate, Ko is not stimulated by cyclic AMP. K1 is poorly stimulated by cyclic AMP (1.3 times), Ku is highly stimulated (6 times). The specificity of KII with respect to various nucleotides and cyclic nucleotides has been determined. K1 and KII account for the total cyclic AMP dependent protein kinase activity in the homogenate.
Similar articles
-
Characterization of cyclic nucleotide-independent protein kinase produced enzymatically from its proenzyme by calcium-dependent neutral protease from rat liver.J Biochem. 1978 Jan;83(1):207-12. doi: 10.1093/oxfordjournals.jbchem.a131893. J Biochem. 1978. PMID: 24046 No abstract available.
-
Characterization of the cyclic AMP-dependent protein kinase from rat pancreas, further purification of the catalytic subunit, substrate specificity, effect of the pancreatic heat stable inhibitor.Biochimie. 1978;60(8):777-85. doi: 10.1016/s0300-9084(78)80022-4. Biochimie. 1978. PMID: 215237
-
Autophosphorylation of cGMP-dependent protein kinase.J Biol Chem. 1981 May 25;256(10):5029-36. J Biol Chem. 1981. PMID: 6262313 No abstract available.
-
Protein kinases in myelin of rat brain: solubilization and characterization.J Neurochem. 1975 Mar;24(3):503-12. doi: 10.1111/j.1471-4159.1975.tb07668.x. J Neurochem. 1975. PMID: 163295 No abstract available.
-
Guanosine 3':5'-monophosphate-dependent protein kinase from bovine cerebellum. Purification and characterization.J Biol Chem. 1975 Jun 25;250(12):4690-5. J Biol Chem. 1975. PMID: 237908
Cited by
-
On the secretagogue effect of dibutyryl cyclic AMP in the rat exocrine pancreas.Pflugers Arch. 1977 Nov 25;372(1):69-76. doi: 10.1007/BF00582208. Pflugers Arch. 1977. PMID: 22842
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Research Materials