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. 1974 Oct;6(4):411-4.
doi: 10.1128/AAC.6.4.411.

Activity of tetracycline, doxycycline, and minocycline against methicillin-susceptible and -resistant staphylococci

Activity of tetracycline, doxycycline, and minocycline against methicillin-susceptible and -resistant staphylococci

J N Minuth et al. Antimicrob Agents Chemother. 1974 Oct.

Abstract

Tetracycline, doxycycline, and minocycline were evaluated for their antibacterial activity against methicillin-susceptible and -resistant isolates of Staphylococcus. At clinically achievable levels both doxycycline and minocycline were more active than tetracycline against methicillin-susceptible organisms. Tetracycline and doxycycline had no activity against methicillin-resistant staphylococci, whereas minocycline at 2 mug/ml inhibited six of 13 strains and, at 3 mug/ml, 10 of 13 strains.

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