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. 2026 Jan 24;14(2):e71940.
doi: 10.1002/ccr3.71940. eCollection 2026 Feb.

A Rare Case of Esophageal Fordyce Spots (EFS) or Ectopic Esophageal Sebaceous Glands (EESG)

Shreya Bollu  1 , Sugandha Bollu  1 , Srikrishna Bollu  2 , Amy Yeung  3 , Elizabeth Eapen  4 , Metin Taskin  4 , Janardhan Bollu  5 , Sita Chokhavatia  6
Affiliations

A Rare Case of Esophageal Fordyce Spots (EFS) or Ectopic Esophageal Sebaceous Glands (EESG)

Shreya Bollu et al. Clin Case Rep. .

Abstract

Ectopic esophageal sebaceous glands are rare, benign lesions that may mimic more serious pathology. Recognition of this condition can prevent unnecessary interventions, guide management focused on symptom control, and provide reassurance to patients.

Keywords: benign; ectopic; esophagus; sebaceous.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
(A, B) Endoscopic images demonstrating EFS in the middle third of the esophagus (yellow arrowheads), resembling benign glycogenic acanthosis. (C) Hematoxylin and eosin–stained section at 40× magnification showing squamous epithelium without associated hair follicles, supporting the ectopic nature of the lesions. (D) Hematoxylin and eosin–stained section at 400× magnification revealing sebaceous glands (blue arrowhead).
See this image and copyright information in PMC

References

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    1. Jeon M. S., Kim G. H., Jeong D. Y., et al., “Magnifying Endoscopy for Esophageal Ectopic Sebaceous Glands,” Clinical Endoscopy 51, no. 5 (2018): 495–497, 10.5946/ce.2017.187. - DOI - PMC - PubMed
    1. Fung B. M., Faulkner C., and David J., “S2295 Epidermoid Metaplasia in the Proximal Esophagus,” American Journal of Gastroenterology 117, no. 10 Suppl (2022): e1546, 10.14309/01.ajg.0000865820.32570.ee. - DOI

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