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. 1966 Feb;10(2):187-91.

Evidence for a humoral thymic factor in rabbits

C A Trench, J W Watson, F C Walker, P S Gardner, C A Green

Evidence for a humoral thymic factor in rabbits

C A Trench et al. Immunology. 1966 Feb.

Abstract

Rabbits thymectomized between 12 and 36 hours after birth subsequently show reduced levels of circulating lymphocytes together with a lowered immunological response to human γ-globulin. These effects of thymectomy can, to a large extent, be prevented by means of intraperitoneal auto-transplants of thymus in a Millipore diffusion chamber. It appears possible that the epithelial-reticular cells of the transplant persist in the diffusion chamber and elaborate a humoral factor, or factors, which take part in the maturation of antibody-producing cells.

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References

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