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. 1966 Jun 17;152(3729):1630-1.
doi: 10.1126/science.152.3729.1630.

Tritiated norepinephrine: release from brain slices by electrical stimulation

R J Baldessarini, I J Kopin

Tritiated norepinephrine: release from brain slices by electrical stimulation

R J Baldessarini et al. Science. .

Abstract

Slices of rat brain and heart that had concentrated H(3)-norepinephrine were superfused and electrically stimulated. Stimulation induced a marked release of H(3)-norepinephrine with a threshold and a maximum repsonse. Release also occurred with increased concentrations of potassium, presumably due to neuronal depolarization. Inhibition of electrically induced release occurred with low calcium and with chlorpromazine and pentobarbital.

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