doi: 10.1099/00221287-104-2-187.
Studies on the chemical composition of lipopolysaccharide from Neisseria meningitidis group B
- PMID: 416170
- DOI: 10.1099/00221287-104-2-187
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Studies on the chemical composition of lipopolysaccharide from Neisseria meningitidis group B
J Gen Microbiol.
1978 Feb.
Abstract
A lipopolysaccharide was isolated from Neisseria meningitidis group B by phenol/water extraction and purified by differential ultracentrifugation. This preparation exhibited endotoxic properties as shown by the limulus-lysate assay. Mild acid hydrolysis of the lipopolysaccharides yielded a lipid A fraction and a polysaccharide fraction. The lipid A fraction contained fatty acids, phosphorus and glucosamine. Analysis of the polysaccharide fraction revealed the presence of glucose, galactose, glucosamine, 2-keto-3-deoxyoctonic acid and phosphorus. There was no heptose.
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