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. 1967 Mar;12(3):313-9.

Electrophoretic studies of the conversion products of serum beta-1C-globulin

C B Laurell, B Lundh

Electrophoretic studies of the conversion products of serum beta-1C-globulin

C B Laurell et al. Immunology. 1967 Mar.

Abstract

By the method of antigen—antibody crossed electrophoresis where the antigens after a first separation in agarose gel are driven into a new antibody containing gel, serum β1C-globulin and its conversion products were analysed in native serum as well as after addition of EDTA, incubation with immunoprecipitate and hydrazine, and after inactivation at 56°.

It is shown that β1C-globulin can be converted not only to β1A-globulin or components with the same mobility as β1A-globulin but also to additional components, one in the α2-region, one in the inter-β-region and one in the γ1-region. α2- and inter-β-components are seen especially in serum to which EDTA has been added. EDTA did not inhibit the spontaneous conversion of β1C-globulin.

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References

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