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Comment
. 2026 Feb 5;391(6785):552-553.
doi: 10.1126/science.aee7270. Epub 2026 Feb 5.

The ovarian stroma as a therapeutic target

Francesca E Duncan  1   2 , Elnur Babayev  1
Affiliations
Comment

The ovarian stroma as a therapeutic target

Francesca E Duncan et al. Science. .

Abstract

A drug with antifibrotic properties may improve fertility.

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  • Antifibrotic drug finerenone restores fertility in premature ovarian insufficiency.
    Lin Z, Li Y, Zhao Y, Liu D, Deng S, Gu J, Li Y, Zhao X, Wu P, Xiao Y, Su J, Sun Y, Zhang Y, Lee YL, Sato Y, Zeng H, Lu H, Zhang J, Ko JKY, Zhao J, Kawamura K, Ng EHY, Jiang S, Li Y, Xia X, Chan KKL, Yeung WSB, Wang TR, Liu K. Lin Z, et al. Science. 2026 Feb 5;391(6785):eadz4075. doi: 10.1126/science.adz4075. Epub 2026 Feb 5. Science. 2026. PMID: 41643022

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