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. 1967 May 19;156(3777):947-8.
doi: 10.1126/science.156.3777.947.

2 types of lambda polypeptide chains in human immunoglobulins

D Ein, J L Fahey

2 types of lambda polypeptide chains in human immunoglobulins

D Ein et al. Science. .

Abstract

Two antigenic subtypes of human lambda polypeptide chains were distinguished by rabbit antiserum produced to a lambda Bence Jones protein. Lambda Bence Jones proteins and G myeloma proteins with lambda light chains were identified as being in one or the other subtype. The Oz (+) lambda chain subtype is present in light chains from pooled normal human immunoglobulin G and in whole normal immunoglobulin G molecules.

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