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. 2026 Feb 9.
doi: 10.1007/s00595-026-03241-z. Online ahead of print.

Impact of laparoscopic sleeve gastrectomy on gut and oral microbiota diversity, weight loss, and the metabolic outcomes

Akira Umemura  1 , Akira Sasaki  2 , Daisuke Sasaki  3 , Akiko Iizuka  3 , Manabu Chiba  3 , Keiko Aihara  3 , Naoko Ubukata  4 , Hideki Kumagai  2 , Yota Tanahashi  2 , Takafumi Iwasaki  2 , Taro Ando  2 , Hiroyuki Nitta  2
Affiliations

Impact of laparoscopic sleeve gastrectomy on gut and oral microbiota diversity, weight loss, and the metabolic outcomes

Akira Umemura et al. Surg Today. .
No abstract available

Keywords: Diversity; Gut microbiota; Laparoscopic sleeve gastrectomy; Metabolic dysfunction associated steatohepatitis; Metabolic surgery; Oral microbiota; Type 2 diabetes.

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Conflict of interest statement

Declarations. Conflict of interest: The authors declare no conflict of interests in association with this article. Ethical approval: The study protocol was approved by the Institutional Review Board of Iwate Medical University Hospital (approval numbers: H27-47, HGH27-27, and MH2022-056). Informed consent was obtained from each patient before enrollment. Patient consent: We obtained informed consent from each patient before enrollment.

References

    1. World Health Organization Obesity and Overweight [Internet]. [(accessed on 27 June 2025)]. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight
    1. Abad-Jiménez Z, Vezza T. Obesity: A global health challenge demanding urgent action. Biomedicines. 2025;13:502. - DOI - PubMed - PMC
    1. Naitoh T, Kasama K, Seki Y, Ohta M, Oshiro T, Sasaki A, et al. Efficacy of sleeve gastrectomy with Duodenal-Jejunal bypass for the treatment of obese severe diabetes patients in japan: a retrospective multicenter study. Obes Surg. 2018;28:497–505. - DOI - PubMed
    1. Umemura A, Sasaki A, Takamura T, Takayama H, Takeshita Y, Toya Y, et al. Relationship between the changes in hepatokine levels and metabolic effects after laparoscopic sleeve gastrectomy in severely obese patients. Surg Today. 2024;54:581–90. - DOI - PubMed
    1. Debédat J, Clément K, Aron-Wisnewsky J. Gut microbiota dysbiosis in human obesity: impact of bariatric surgery. Curr Obes Rep. 2019;8:229–42. - DOI - PubMed

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