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. 1967 May;190(2):261-72.
doi: 10.1113/jphysiol.1967.sp008206.

Gastric secretion during pregnancy and lactation in the rat

B Lilja, S E Svensson

Gastric secretion during pregnancy and lactation in the rat

B Lilja et al. J Physiol. 1967 May.

Abstract

1. Gastric acid secretion has been studied in the rat before, during and after pregnancy using different types of stomach preparation. During the same periods the histamine-forming capacity (HFC) has been determined in gastric mucosa and mammary gland.2. In rats with a whole stomach fistula interdigestive acid secretion is increased during pregnancy and lactation.3. In rats with a denervated chronic pouch secretory response to stimulation with gastrin and histamine is augmented during pregnancy and lactation.4. The histamine forming capacity (HFC) of the gastric mucosa is increased 2-3 times during the last days of pregnancy and also during lactation.5. The HFC of the mammary gland is increased 2-3 times during lactation as compared with the fully developed gland in pregnancy.

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