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. 2026 Feb 14.
doi: 10.1186/s12870-026-08336-w. Online ahead of print.

Enhancing heritable genome editing in soybean by optimizing promoter combinations for the LbCas12a system

Jay Lv  1 , Lizhao Geng  1 , Wan Shi  2 , Chao Li  1 , Songyuan Wang  1 , Boqi Zhang  1 , Kun Yu  1 , Ruijie Cui  1 , Yubo Liu  1 , Feng Xiong  1 , Jian Lv  1 , Shujie Dong  3 , Brenden Barco  3 , Jianping Xu  4
Affiliations

Enhancing heritable genome editing in soybean by optimizing promoter combinations for the LbCas12a system

Jay Lv et al. BMC Plant Biol. .
No abstract available

Keywords: Heritable genome editing; LbCas12a; Promoter optimization; Soybean; Threshold.

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Conflict of interest statement

Declarations. Ethics approval and consent to participate: Not applicable. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

References

    1. Baker M. Gene-editing nucleases. Nat Methods. 2012;9(1):23–6.
    1. Liu G, Lin Q, Jin S, Gao C. The CRISPR-Cas toolbox and gene editing technologies. Mol Cell. 2022;82(2):333–47.
    1. Wang JY, Doudna JA. CRISPR technology: A decade of genome editing is only the beginning. Science. 2023;379(6629):eadd8643.
    1. Anzalone AV, Koblan LW, Liu DR. Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors. Nat Biotechnol. 2020;38(7):824–44.
    1. Zetsche B, Gootenberg Jonathan S, Abudayyeh Omar O, Slaymaker Ian M, Makarova Kira S, Essletzbichler P, Volz Sara E, Joung J, van der Oost J, Regev A, et al. Cpf1 is a single RNA-Guided endonuclease of a class 2 CRISPR-Cas system. Cell. 2015;163(3):759–71.