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Review
. 2026 Mar;53(1):37-50.
doi: 10.1016/j.ogc.2025.09.004. Epub 2025 Dec 22.

Beyond Infection: Targeting Maternal Sepsis

Affiliations
Review

Beyond Infection: Targeting Maternal Sepsis

Laurence E Shields et al. Obstet Gynecol Clin North Am. 2026 Mar.

Abstract

Although sepsis only occurs in 1 to 2.5 per 1,000 births, it represents 11-23% of maternal deaths-many of which are preventable. Due to the high morbidity and mortality associated with sepsis, the Surviving Sepsis Campaign (SSC) recommends that every hospital develop a process to screen for sepsis and a standard operating procedures for treatment. The purpose of this report is to review the most recent SSC guidelines with particular reference to maternal physiology, highlight maternal-specific screening tools, and recommendations for treatment, including the need for multidisciplinary collaborative care to reduce morbidity and mortality from maternal sepsis.

Keywords: Early warning signs; Guidelines; Maternal sepsis; Surviving sepsis campaign.

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Conflict of interest statement

Disclosure None.

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