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. 2026 Feb 16.
doi: 10.1186/s12872-026-05623-0. Online ahead of print.

Premature "asymptomatic" peripheral artery disease and correlates among HIV-positive adults in Ghana: findings from the SCRIPT study

Lambert Tetteh Appiah  1   2   3 , Jacob Solomon Idan  4 , Samuel Blay Nguah  4 , Sowah Tetteh  5 , Shadrack Osei Asibey  5 , Dzifa Ahadzi  6 , Martin Agyei  5 , Betty Norman  5 , Michael K Amponsah  7 , Alexis Okoh  8 , Jonathan Stiles  9 , Bert-Jan van den Born  10 , Charles Agyemang  10 , Fred Stephen Sarfo  5
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Free article

Premature "asymptomatic" peripheral artery disease and correlates among HIV-positive adults in Ghana: findings from the SCRIPT study

Lambert Tetteh Appiah et al. BMC Cardiovasc Disord. .
Free article
No abstract available

Keywords: Cardiovascular disease; Ghana; HIV; Peripheral artery disease; Risk factors.

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Conflict of interest statement

Declarations. Ethics approval and consent to participate: The study was conducted in accordance with the ethical principles of the Declaration of Helsinki. The protocol was approved by the Committee on Human Research, Publication and Ethics (CHRPE) of the KNUST School of Medicine and Dentistry (Reference: CHRPE/AP/509/18) in 2018. The study adhered to the STROBE guidelines for cross-sectional studies. Written informed consent was obtained from all participants in their preferred language (English or Twi). To ensure confidentiality, all data were anonymized. Participants with newly identified cardiovascular risk factors received counseling and were referred for appropriate clinical care. Competing interests: The authors declare no competing interests.

References

    1. Owusu AY, Asante KT. Current HIV / AIDS status, access to antiretroviral treatment, and HIV-related stigma in Ghana. Institute of Statistical, Social and Economic Research. 2020;6:1–5.
    1. Roomaney RA, Wyk B, Wyk VP. Aging with HIV: increased risk of HIV comorbidities in older adults. Int J Environ Res Public Health. 2022;19:2359.
    1. Henning RJ, Greene JN. The epidemiology, mechanisms, diagnosis and treatment of cardiovascular disease in adult patients with HIV. Am J Cardiovasc Dis. 2023;13:101–21.
    1. Shah ASV, Stelzle D, Lee KK, et al. Global burden of atherosclerotic cardiovascular disease in people living with HIV: systematic review and Meta-Analysis. Circulation. 2018;138:1100–12.
    1. Gupta N, Bajaj S. The prevalence of peripheral arterial disease in HIV patients. J Vasc Med Surg. 2013. https://doi.org/10.4172/2329-6925.1000118.

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