Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Mar;19(3):1092-6.
doi: 10.1128/iai.19.3.1092-1096.1978.

Toxicity of Pseudomonas aeruginosa exotoxin A for human macrophages

M Pollack, S E Anderson Jr

Toxicity of Pseudomonas aeruginosa exotoxin A for human macrophages

M Pollack et al. Infect Immun. 1978 Mar.

Abstract

Pseudomonas aeruginosa exotoxin A was toxi in vitro for human peripheral blood macrophages. Cytotoxicity, manifested by morphological evidence of cell death and inhibition of [3H]thymidine uptake, followed exposure to as little as 10 ng of exotoxin per ml for 1 h. In addition, phagocytosis of heat-killed Candida albicans by macrophages exposed to sublethal concentrations of exotoxin was impaired. This cytotoxicity was neutralizable with antiexotoxin serum.

PubMed Disclaimer

References

    1. Can J Microbiol. 1977 Feb;23(2):183-9 - PubMed
    1. Infect Immun. 1977 Dec;18(3):596-602 - PubMed
    1. Infect Immun. 1978 Jan;19(1):29-33 - PubMed
    1. Infect Immun. 1977 Mar;15(3):776-80 - PubMed
    1. J Clin Microbiol. 1977 Jul;6(1):58-61 - PubMed

LinkOut - more resources