Lymphocyte functions and subpopulation distribution in marmosets

Abstract

Marmoset lymphocytes were highly reactive to general mitogens, participate in direct cytotoxicity (purportedly mediated by T-cells) and particpate in an antibody dependent lymphocyte cytotoxicity assay (K-cell). The distribution of lymphocyte subpopulations among various species showed that the percent T-cells ranged from 46.4 to 66.6% in different species while complement receptor cells ranged from 10.3 to 19.0%. Surface immunoglobulin (SIg) stable B-cells ranged from 10.6 to 16.4% while the SIg labile L-cells ranged from 26.9 to 37.5%. A fourth receptor, Fc, was demonstrated on 23.7 to 31.7% of the marmoset lymphocytes.