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. 1968 Apr;107(4):559-64.
doi: 10.1042/bj1070559.

Comparative studies of two types of bovine immunoglobulin G heavy chains

C P Milstein, A Feinstein

Comparative studies of two types of bovine immunoglobulin G heavy chains

C P Milstein et al. Biochem J. 1968 Apr.

Abstract

;Fingerprints' of bovine colostrum and serum immunoglobulin G1 heavy chains were extremely similar, but different from serum immunoglobin G2 heavy chains. Serum immunoglobulin G1 and immunoglobulin G2 heavy chains were treated with cyanogen bromide. The fractions from the C-terminal end of the heavy chains were isolated and the amino acid sequence of this fraction from immunoglobulin G2 was:His-Glx-Ala-Leu-His-Asx-His-Tyr-Met-Gln-Lys-Ser-Thr-Ser-Lys-Ser-Ala-GlyThe amino acid composition of this fraction from immunoglobulin G1 was the same except for the methionine, which in immunoglobulin G1 was replaced by threonine.

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References

    1. Biochem J. 1966 May;99(2):356-66 - PubMed
    1. Nature. 1966 Aug 6;211(5049):591-3 - PubMed
    1. Proc Natl Acad Sci U S A. 1966 Aug;56(2):602-7 - PubMed
    1. Nature. 1966 Oct 8;212(5058):205-6 - PubMed
    1. Biochim Biophys Acta. 1967 Feb 21;133(2):369-70 - PubMed