Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2026 Feb 26.
doi: 10.1038/s41598-026-41509-z. Online ahead of print.

Scalable flow synthesis of ultrasmall inorganic nanoparticles for biomedical applications via a confined impinging jet mixer

Andrea C Kian  1 , Mahima Gupta  2 , Heeju Hong  3 , Kálery La Luz Rivera  4 , Nil Pandey  2   5 , Katherine J Mossburg  1 , Derick N Rosario-Berrios  2 , Portia S N Maidment  2 , Andrew R Hanna  1 , Priyash Singh  2 , Zhenting Xiang  5   6 , Jay Kikkawa  7 , David Issadore  1 , Andrew D A Maidment  2 , Hyun Koo  1   5   6 , David P Cormode  8   9   10   11
Affiliations
Free article

Scalable flow synthesis of ultrasmall inorganic nanoparticles for biomedical applications via a confined impinging jet mixer

Andrea C Kian et al. Sci Rep. .
Free article
No abstract available

Keywords: Cerium oxide; Iron oxide; Microfluidics; Nanoparticles; Silver sulfide; Silver telluride.

PubMed Disclaimer

Conflict of interest statement

Declarations. Competing interests: DPC and ADAM are named as inventors on patent applications concerning silver-based contrast agents. They also hold stock in Daimroc Imaging, a company that is seeking to commercialize such agents. DPC and HK are named as inventors on patent applications concerning iron oxide-based nanoparticles. DI is named as an inventor on patent applications concerning methods of microfluidic nanoparticle production.

References

    1. Anselmo, A. C. & Mitraotri, S. A. Review of clinical translation of inorganic nanoparticles. AAPS J. 17, 5, 1041–1054 (2015).
    1. Huang, H. C., Barua, S., Sharma, G., Dey, S. K. & Rege, K. Inorganic nanoparticles for cancer imaging and therapy. J. Controlled Release. 155, 3, 344–357 (2011).
    1. Kim, T. & Hyeon, T. Applications of inorganic nanoparticles as therapeutic agents. Nanotechnology 25, 1, 012001 (2014).
    1. Zarschlet, K. et al. Ultrasmall inorganic nanoparticles: State-of-the-art and perspectives for biomedical applications. Nanomedicine 12, 6, 1663–1701 (2016).
    1. Ehlerding, E. B., Chen, F. & Cai, W. Biodegradable and renal clearable inorganic nanoparticles. Adv Sci. (Weinheim Ger). 3, 1500223 (2016).

LinkOut - more resources