Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1978 Feb;13(2):284-8.
doi: 10.1128/AAC.13.2.284.

Activity of amantadine, rimantadine, and ribavirin against swine influenza in mice and squirrel monkeys

G H Scott, E L Stephen, R F Berendt
Comparative Study

Activity of amantadine, rimantadine, and ribavirin against swine influenza in mice and squirrel monkeys

G H Scott et al. Antimicrob Agents Chemother. 1978 Feb.

Abstract

Amantadine, rimantadine, and ribavirin given orally, either prophylactically or therapeutically, reduced mortality and increased the survival time of 3-week-old mice infected with the type A/New Jersey/8/76 (swine) strain of influenza virus. In addition, amantadine and rimantadine, administered therapeutically, increased the rate of virus clearance from lungs of infected mice. Administration of amantadine either before or after virus challenge ameliorated the illness in squirrel monkeys; when administered therapeutically, it appeared to eliminate virus shedding from infected monkeys within hours after therapy was initiated.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Virology. 1965 Jun;26:262-9 - PubMed
    1. Infect Immun. 1977 May;16(2):476-9 - PubMed
    1. Antimicrob Agents Chemother. 1976 Sep;10(3):549-54 - PubMed
    1. J Infect Dis. 1976 Nov;134(5):516-27 - PubMed
    1. Infect Immun. 1976 Mar;13(3):696-703 - PubMed

Publication types

LinkOut - more resources