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Clinical Trial
. 1968 Nov 23;4(5629):477-9.
doi: 10.1136/bmj.4.5629.477.

Prevention of rhesus immunization. A controlled clinical trial with a comparatively low dose of anti-D immunoglobulin

C Dudok de Wit, E Borst-Eilers, C M Weerdt, G J Kloosterman
Clinical Trial

Prevention of rhesus immunization. A controlled clinical trial with a comparatively low dose of anti-D immunoglobulin

C Dudok de Wit et al. Br Med J. .

Abstract

A controlled clinical trial was carried out to test the effectiveness of a comparatively low dose of anti-D immunoglobulin (250 mug) in preventing rhesus immunization.In the control group 17 out of 329 women (5%) formed rhesus antibodies, whereas in the treated group only 3 out of 333 women (0.9%) showed active immunization, all three of whom had an exceptionally large transplacental bleeding.

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References

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