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. 1968 Nov 8;162(3854):672-3.
doi: 10.1126/science.162.3854.672.

C'3 synthesis in the human fetus and lack of transplacental passage

R P Propp, C A Alper

C'3 synthesis in the human fetus and lack of transplacental passage

R P Propp et al. Science. .

Abstract

Allotypic differences in the third component of complement between mothers and their newborns provided evidence for synthesis of this complement component by the fetus. There was no indication that this protein traversed the placenta. The known low level of C'3 in the neonate was confirmed, and the maternal concentration was found to be significantly elevated.

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