[The hypothesis of the genetic transmission (autosomal recessive) of subtypes of HBs Ag. The example of Kel Kummer]
- PMID: 417847
[The hypothesis of the genetic transmission (autosomal recessive) of subtypes of HBs Ag. The example of Kel Kummer]
Abstract
In a study of asymtomatic carriers of hepatitis B surface antigen (HBs Ag) in a closed population, the Twareg Kel Kummer, 18% of the population (79 individuals out of 439 tested) were found to be carriers of one of the 3 sub types: HBs Ag/a2 1 dw, HBs Ag/a2 1 yw and HBs Ag/a3 yw. Evidence from genealogies and the distribution of carriers in the pyramid of ages strongly supports the hypothesis of genetic transmission of the gene sub type as an autosomal recessive.