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. 1978 Apr;16(3):480-4.

Structure and ribonucleoprotein staining of kinetochores of colchicine-treated HeLa cells

E Bielek
  • PMID: 417951

Structure and ribonucleoprotein staining of kinetochores of colchicine-treated HeLa cells

E Bielek. Cytobiologie. 1978 Apr.

Abstract

HeLa cells treated with colchicine show a lengthening of kinetochores lacking an inner layer. Combined EDTA- and ribonuclease treatment (BERNHARD 1969) indicate the presence of ribonucleoprotein in the dense outer layer as well as in the surrounding fine fibrillar mass. Reconstructions from serial sections reveal a band-like enlargement of these layers around the primary constriction during the inhibition of mitosis by colchicine.

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