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. 1967 Dec;1(6):1255-64.
doi: 10.1128/JVI.1.6.1255-1264.1967.

Vaccinia virus infection of synchronized pig kidney cells

R M Groyon, A J Kniazeff

Vaccinia virus infection of synchronized pig kidney cells

R M Groyon et al. J Virol. 1967 Dec.

Abstract

Vaccinia virus replication was studied in pig kidney (PK-15) cells synchronized by excess thymidine treatment. It was found that virus replication with concomitant inhibition of mitosis can occur at any period in the life cycle of the cell except for the narrow span of time from late prophase through telophase. Cells infected at this time continue to divide, and vaccinia does not replicate until cell division is complete.

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