Effects of mutational loss of specific intracellular proteases on the sporulation of Bacillus subtilis
- PMID: 4196247
- PMCID: PMC251816
- DOI: 10.1128/jb.114.2.612-617.1973
Effects of mutational loss of specific intracellular proteases on the sporulation of Bacillus subtilis
Abstract
Two protease-deficient mutants of Bacillus subtilis 168 (Trp(-)) were isolated and compared with the parental strain with respect to production of intracellular proteases and sporulation. A mutant lacking the metal-requiring "neutral" protease intracellularly sporulated as well as the parental strain. A second mutant, deficient in an as yet uncharacterized intracellular protease, failed to sporulate normally. It is proposed that this new protease is also involved in intracellular protein turnover.
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