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. 1973 Mar;70(3):641-5.
doi: 10.1073/pnas.70.3.641.

Contraction of isolated smooth-muscle cells--structural changes

Contraction of isolated smooth-muscle cells--structural changes

F S Fay et al. Proc Natl Acad Sci U S A. 1973 Mar.

Abstract

The contraction of isolated smooth-muscle cells has been correlated with evagination of the cell membrane, a marked change in myofilament orientation, and a decrease in cellular volume. Both localized and full contractions have been elicited in the same cell by varying the intensity of electrical stimulation. These results may be explained by a model of the smooth-muscle cell in which the contractile apparatus extends between attachment sites on the cell membrane that are relatively closely spaced.

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References

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