Contraction of isolated smooth-muscle cells--structural changes
- PMID: 4197624
- PMCID: PMC433324
- DOI: 10.1073/pnas.70.3.641
Contraction of isolated smooth-muscle cells--structural changes
Abstract
The contraction of isolated smooth-muscle cells has been correlated with evagination of the cell membrane, a marked change in myofilament orientation, and a decrease in cellular volume. Both localized and full contractions have been elicited in the same cell by varying the intensity of electrical stimulation. These results may be explained by a model of the smooth-muscle cell in which the contractile apparatus extends between attachment sites on the cell membrane that are relatively closely spaced.
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