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. 1973 Jul;70(7):1950-4.
doi: 10.1073/pnas.70.7.1950.

Crossing-over between X AND Y chromosomes during ribosomal DNA magnification in Drosophila melanogaster

F Ritossa

Crossing-over between X AND Y chromosomes during ribosomal DNA magnification in Drosophila melanogaster

F Ritossa. Proc Natl Acad Sci U S A. 1973 Jul.

Abstract

In genetic combinations undergoing ribosomal DNA magnification, the frequency of crossing-over between X and Y chromosomes is increased at least 20-fold above that in similar combinations not undergoing magnification. Such recombination occurs at the ribosomal DNA level. The data are consistent with a model where extra copies of ribosomal DNA are formed which, after circularization, are integrated into the chromosome.

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