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Case Reports
. 1979 Feb 15;45(2):133-40.
doi: 10.1007/BF00691891.

[Electron microscopic and neurochemical study of Alexander's disease (author's transl)]

[Article in French]
R Escourolle, C de Baecque, F Gray, N Baumann, J J Hauw
Case Reports

[Electron microscopic and neurochemical study of Alexander's disease (author's transl)]

[Article in French]
R Escourolle et al. Acta Neuropathol. .

Abstract

The authors report the results of a cerebral and of a neuromuscular biopsies and of the autopsy findings in another infantile case of Alexander's disease in a girl. They review the 17 previously reported cases of this disease and the various etiopathogenic hypotheses mentioned. The presence of numerous, sometimes abnormal enlarged mitochondria and of abundant membranous cytoplasmic bodies in the astrocytic cytoplasm seems to be unreported elsewhere. Peripheral nerve changes are mentioned for the first time.

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