doi: 10.1126/science.182.4117.1136.
Direct evidence for a colchicine-induced impairment in the mobility of membrane components
- PMID: 4201508
- DOI: 10.1126/science.182.4117.1136
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Direct evidence for a colchicine-induced impairment in the mobility of membrane components
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Abstract
Freeze-etch electron microscopy was used to show that colchicine interacts with membranes of the ciliate protozoan Tetrahymena pyriformis. Colchicine impairs the temperature-induced translational and vertical mobility of the membrane-intercalating particles of the freeze-fractured alveolar membranes lying just below the plasma membranes.
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