doi: 10.1073/pnas.70.12.3339.
The presence of ribonucleotides in mature closed-circular mitochondrial DNA
- PMID: 4202844
- PMCID: PMC427232
- DOI: 10.1073/pnas.70.12.3339
Item in Clipboard
The presence of ribonucleotides in mature closed-circular mitochondrial DNA
Proc Natl Acad Sci U S A.
1973 Dec.
Abstract
Mitochondrial DNA from mouse and HeLa cells is nicked by alkali and chick-embryo ribonuclease H. It has been concluded that ribonucleotides are present in the closed-circular duplex. A comparative study of the scission rates at pH 13.0 of RNA and of mitochondrial DNAs indicates that there are no more than 10 ribonucleotides in the major fraction of the mitochondrial DNAs.
Similar articles
-
Ribonucleotides in closed circular mitochondrial DNA from HeLa cells.Biochem Biophys Res Commun. 1973 Jul 2;53(1):140-8. doi: 10.1016/0006-291x(73)91412-5. Biochem Biophys Res Commun. 1973. PMID: 4582369 No abstract available.
-
RNase and alkali sensitivity of closed circular mitochondrial DNA of rat ascites hepatoma cells.Biochem Biophys Res Commun. 1973 Jan 23;50(2):252-8. doi: 10.1016/0006-291x(73)90833-4. Biochem Biophys Res Commun. 1973. PMID: 4347514 No abstract available.
-
Closed circular DNAs with tandem repeats of a sequence from polyoma virus.Virology. 1974 Sep;61(1):140-55. doi: 10.1016/0042-6822(74)90249-9. Virology. 1974. PMID: 4369867 No abstract available.
-
Transcription of supercoiled mitochondrial DNA by bacterial RNA polymerase.Eur J Biochem. 1974 Sep 1;47(2):225-34. doi: 10.1111/j.1432-1033.1974.tb03686.x. Eur J Biochem. 1974. PMID: 4607306 No abstract available.
-
Structure and function of kinetoplast DNA.J Protozool. 1973 Feb;20(1):2-8. doi: 10.1111/j.1550-7408.1973.tb05993.x. J Protozool. 1973. PMID: 4571786 Review. No abstract available.
Cited by
-
DNA extraction procedures meaningfully influence qPCR-based mtDNA copy number determination.Mitochondrion. 2009 Jul;9(4):261-5. doi: 10.1016/j.mito.2009.03.003. Epub 2009 Mar 24. Mitochondrion. 2009. PMID: 19324101 Free PMC article.
-
On the early emergence of reverse transcription: theoretical basis and experimental evidence.J Mol Evol. 1992 Dec;35(6):524-36. doi: 10.1007/BF00160213. J Mol Evol. 1992. PMID: 1282161
-
One, No One, and One Hundred Thousand: The Many Forms of Ribonucleotides in DNA.Int J Mol Sci. 2020 Mar 2;21(5):1706. doi: 10.3390/ijms21051706. Int J Mol Sci. 2020. PMID: 32131532 Free PMC article. Review.
-
Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model.Nucleic Acids Res. 2017 Dec 15;45(22):12808-12815. doi: 10.1093/nar/gkx1009. Nucleic Acids Res. 2017. PMID: 29106596 Free PMC article.
-
Strand breakage in solutions of DNA and ethidium bromide exposed to visible light.Nucleic Acids Res. 1977;4(5):1393-407. doi: 10.1093/nar/4.5.1393. Nucleic Acids Res. 1977. PMID: 896466 Free PMC article.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
